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  1. Type 2 diabetes - Symptoms and causes - Mayo Clinic

    Feb 27, 2025 · Type 2 diabetes happens when the body cannot use insulin correctly and sugar builds up in the blood. It was once called adult-onset diabetes. Over time, high blood sugar levels in type 2 …

  2. Pathophysiology of Type 2 Diabetes Mellitus - PMC

    This review analyzes the key aspects of T2DM, as well as the molecular mechanisms and pathways implicated in insulin metabolism leading to T2DM and insulin resistance.

  3. Type 2 diabetes - Wikipedia

    Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [6] . Common …

  4. Type 2 diabetes mellitus - Harvard Health

    May 7, 2024 · Type 2 diabetes occurs when your body's cells resist the normal effect of insulin, which is to drive glucose in the blood into the inside of the cells. This condition is called insulin resistance. As …

  5. Type 2 Diabetes: What It Is, Causes, Symptoms & Treatment

    Nov 21, 2025 · Healthy blood sugar (glucose) levels are 70 to 99 milligrams per deciliter (mg/dL). If you have undiagnosed Type 2 diabetes, your levels are typically 126 mg/dL or higher. This condition is …

  6. Type 2 diabetes mellitus | Nature Reviews Disease Primers

    Jul 23, 2015 · Type 2 diabetes mellitus (T2DM) is characterized by dysregulation of carbohydrate, lipid and protein metabolism, and results from impaired insulin secretion, insulin resistance or a …

  7. Understanding Type 2 Diabetes | ADA

    Learn about type 2 diabetes, a chronic condition that affects blood glucose. Understand type 2 symptoms, causes, and detection. Take our 60- second type 2 risk test.

  8. Type 2 Diabetes | Diabetes | CDC

    May 15, 2024 · About 1 in 10 Americans has diabetes; most have type 2. More children, teens, and young adults are developing type 2 diabetes than in the past. Type 2 diabetes can be prevented or …

  9. Type 2 Diabetes - NIDDK

    Managing your blood glucose, blood pressure, and cholesterol, and quitting smoking if you smoke, are important ways to manage your type 2 diabetes.

  10. Type 2 Diabetes Mellitus: Background, Pathophysiology, Etiology

    Sep 25, 2025 · Type 2 diabetes mellitus consists of an array of dysfunctions characterized by hyperglycemia and resulting from the combination of resistance to insulin action, inadequate insulin …