Spastic ataxia is characterized by the combination of cerebellar ataxia with spasticity and other pyramidal features. It is the hallmark of some hereditary ataxias, but it can also occur in some …

Ataxia and spasticity can coexist in a large number of congenital, genetic or acquired conditions including common conditions such as stroke, multiple sclerosis (MS), cerebral palsy and head …

Jan 1, 2024 · The hereditary spastic paraplegias (HSPs) are a large group of highly diverse, inherited disorders that share the common feature of lower extremity spasticity and weakness. …

Autosomal recessive spastic ataxia of Charlevoix-Saguenay, more commonly known as ARSACS, is a condition affecting muscle movement. People with ARSACS typically have abnormal …

Spastic ataxia is also a feature of autosomal recessive spastic ataxia of Charlevoix-Saguenay. In terms of frequency, Friedreich’s ataxia and SPG7 are followed by ataxia with oculomotor …

Spastic paraplegia type 7 (SPG7) is caused by a genetic mutation that is passed on from parents to their children. It is also sometimes called hereditary spastic paraplegia type 7 (HSPG7). …

The concept of a continuous ataxia-spasticity disease spectrum is further supported by ataxias and hereditary spastic paraplegias sharing not only overlapping phenotypes and underlying …

Hereditary spastic paraplegia (HSP) and spinocerebellar ataxia (SCA) are two such disease entities with an often overlapping presentation, in which next generation exome sequencing …

The spastic ataxia phenotype spectrum includes patients with predominant cerebellar ataxia on one end of the disease continuum and spastic paraplegia on the other, or vice-versa, …

Jan 1, 2018 · The presence of spasticity and pyramidal features is a hallmark of some of hereditary ataxias, such as autosomal-recessive spastic ataxia of Charlevoix–Saguenay, other …