Good managers set the tone for the whole team, encouraging positive behavior from everyone around them. In the November 5 Nature, scientists introduce a subtype of microglia that appears to do just ...
Hypertension heightens the risk of Alzheimer’s disease, but exactly how is not understood. In a bioRxiv preprint posted September 19, scientists led by Costantino Iadecola at Weill Cornell Medical ...
This knock-in (KI) mouse model was generated by introducing a D427V point mutation into exon 10 of the mouse Gba1 (glucosidase, beta, acid 1) gene, which corresponds to the human D409V mutation (The ...
This APP transgenic overexpresses mutant human APP under the control of the Thy-1.2 promoter, driving neuronal expression. The transgene carries two mutations associated with familial Alzheimer’s ...
Building 114, Suite 2011 16th Street Charlestown, MA02129 United States Visit Website Contact: Bradley T. Human, M.D., Ph.D. Phone: (617) 726-3987 E-mail: [email protected] Brain Banks Home ...
In September 2016, the Cocoa Supplement and Multivitamin Outcomes Study of Cognition (COSMOS-Mind) began enrolling 2,262 people 65 or older without dementia to evaluate the effect of three years of ...
Whether a person eats a cookie or devours the whole box could come down to the mood of microglia in their hypothalamus. Blocking activation of the region’s NLRP3 inflammasome could keep excessive ...
Contact Information Subodh Verma, M.D., Ph.D., FRCSC, FAHA, FCAHS Toronto, CanadaProfessional Information ProfessorUniversity of Toronto ...
For people with cerebral amyloid angiopathy (CAA), the heightened risk of ARIA, i.e., inflammation around blood vessels, may outweigh any potential gains of anti-amyloid immunotherapy. But with about ...
In the Alzheimer’s brain, microglia diversify into several activation states. What controls this specialization? In a preprint posted to bioRxiv on October 13, scientists led by Martin Kampmann at the ...
Could stem cells step in to replace lost neurons in Parkinson’s disease? In three Phase 1 clinical trials, scientists tested lab-grown dopaminergic cells in small cohorts to assess safety and look for ...
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