Vertical gaze was intact, ... Notice the bilateral horizontal gaze palsy with full ductions in the vertical directions. The patient, converging on a pen at near. MRI 1 year later.

Patients with PSP often had severe postural instability at onset, symmetric parkinsonism, vertical supranuclear gaze palsy, speech and frontal lobe-type features.

A diagnosis of vertical gaze palsy was made, and the patient was referred for neurological evaluation, which was reported to be normal. Figure 1 Clinical photograph of the patient showing ...

- Topline supports moving to Phase 3 trial and shows potential to develop GV1001 as the world's first PSP treatment SEOUL, South Korea, Oct. 29, 2024 /PRNewswire/ -- GemVax & KAEL Co., Ltd ...

Adult-onset NPC is usually associated with several movement disorders such as cerebellar ataxia, dystonia, and chorea, as well as vertical supranuclear gaze palsy and restricted downgaze.

Progressive supranuclear palsy (PSP) is a rare brain disorder that affects approximately 6 in 100,000 people worldwide. It causes muscle weakness and affects gait, balance and overall movement, as ...

GemVax’s phase 2a study ran for 24 weeks and enrolled 78 patients with PSP across five centers in Korea. Patients received either placebo, GV1001 0.56 mg or GV1001 1.12 mg, the company said.

Progressive supranuclear palsy (PSP) is characterized by progressive postural instability with falls, pseudobulbar palsy, axial parkinsonism, supranuclear vertical gaze palsy, executive ...

PSP is a degenerative disease that, like Parkinson's disease, causes symptoms such as gait disturbances, early falls, vertical gaze palsy, rigidity, tremors, and cognitive decline, ...