The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

Hamas urged Jordan to release members of a reported Muslim Brotherhood terrorist cell, who were arrested last week by the Jordanian Intelligence, after being accused of attempting to manufacture ...

HEK293T cells were cultured in DMEM (Corning ... or HMGCR (Addgene, Cat# 86085) by using Lipofectamine 3000™ Transfection Reagent (ThermoFisher, Cat# L3000008). The cells were subsequently treated ...

HEK293T and HEK293TT cells were transiently transfected with plasmids ... while HeLa cells were transfected with Lipofectamine 2000 (Invitrogen, USA). Both transfection reagents were applied at ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neurotoxins derived from animal venoms are ...

By binding to an AKAP11 scaffold, PKA engages in poorly understood interactions with autophagy, a key degradation pathway for neuronal cell homeostasis. Mutations in AKAP11 promote schizophrenia and ...

Chinese solar module manufacturer Longi has revealed it achieved a power conversion efficiency of 34.85% for a two-terminal tandem perovskite solar cell. The U.S. Department of Energy's National ...

5 puro (Addgene) and confirmed via sequencing analysis. Lentivirus was produced by transient co‐transfection of HEK293T cells with a lentivirus vector, packaging plasmid, psPAX2, and pMD2.G using PEI ...

These movements are difficult for people with Parkinson’s disease. The disorder eats away at brain cells—called dopamine neurons—that control movement and emotion. Symptoms begin with tremors. Then ...

A Japanese hospital said Monday it has completed a clinical test to transplant induced pluripotent stem cells that produce insulin to treat a patient with type 1 diabetes, in a step that could ease ...