Adding atezolizumab and bevacizumab to TACE can improve outcomes in previously untreated, unresectable HCC, data suggest.

Metabolic-associated fatty liver disease is prevalent in children and adolescents with severe obesity, with higher insulin resistance and more metabolic syndrome components.

Dear Support, While trying to covalently add ligand to aspartate group, both to OD1 (the OH oxygen) and to OD2 (the C=O oxygen) I've gor a final 4-bonds connections between the igand atom and BOTHs ...

A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and ...

A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and ...

MAHWAH, N.J., April 16, 2025 /PRNewswire/ -- Glenmark Pharmaceuticals Inc., USA (Glenmark) is pleased to announce the upcoming launch [1] of Dextroamphetamine Saccharate, Amphetamine Aspartate, ...

Glenmark Pharmaceuticals Inc., USA to launch Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate and Amphetamine Sulfate Tablets (Mixed Salts of a Single Entity ...

Our initial investigation focused on whether mitochondrial citrate metabolism influences ferroptosis susceptibility. Within mitochondria, citrate synthase (CS) catalyzes the formation of citrate from ...

Aspartate is an amino acid (a protein building block) that has very low concentrations in blood plasma but, surprisingly, very high concentrations in the lungs of mice with metastatic breast cancer.

Aspartate plays important roles in the body, including in the lungs. As an amino acid, it’s one of the building blocks of proteins, crucial to the structure and function of lung cells.

The product of PC, oxaloacetate, has three major metabolic fates: 1) feeding the TCA cycle via citrate synthase as discussed above, 2) conversion to aspartate by glutamatic-oxaloacetic transaminase 2 ...