Motor neuron disease (MND) is the third commonest adult onset neurodegenerative disorder, with an annual incidence of two per 100 000 and prevalence of five to seven per 100 000. 1 MND leads to ...

Recently, it has been demonstrated that overexpression by vascular smooth muscle cells (VSMC) of the versican variant V3, which lacks GAG chains, induces elastin synthesis and fiber deposition in ...

Engineering tissue-like scaffolds that can mimic the microstructure, architecture, topology, and mechanical properties of native tissues while offering an excellent environment for cellular growth has ...

Three iso-energetic and iso-nitrogenous diets were fed to finishing pigs for 28 days to investigate the mammalian target of rapamycin (mTOR) and ubiquitin–proteasome signaling pathways of skeletal ...

This reflects extensive reduction of functional motor units and is morphologically correlated with loss of MNs in the lateral TA/GC motor pool (8), loss of axons in lumbar ventral nerve roots (Fig. 2 ...

Motor neuron disease (MND) is a devastating condition that causes progressive muscle weakness by damaging the motor neurons, the nerve cells that connect the brain to muscles. These neurons allow us ...

Segmental distribution of the motor neuron columns that supply the rat hindlimb: a muscle/motor neuron tract-tracing analysis targeting the motor end plates. Neuroscience 307, 98–108. doi: ...

Recognize the symptoms of this difficult conditionM otor neuron disease (MND), often referred to by the name of one of its varieties, ALS, is a degenerative condition that affects the brain and spinal ...

People who use common psychiatric medications are more likely to develop amyotrophic lateral sclerosis - the most common form of motor neurone disease (MND), according to international researchers who ...

Motor neuron disease usually refers to amyotrophic lateral sclerosis, but it can also refer to other kind of neurodegenerative disease that affect the motor neurons, such as progressive primary ...

Wrist-based accelerometry may be a feasible method for continuous monitoring for individuals with motor neuron disease, according to data published in eBioMedicine.“Actigraphy, which leverages ...