Familial pure dominant spastic paraplegia (SPG) is a clinically and genetically heterogeneous group of neurodegenerative disorders, mainly characterised by spasticity of the lower limbs. Gait ...

Researchers at the University of Basel have developed a gene therapy that could potentially treat a rare and currently fatal ...

Generalized myasthenia gravis (gMG) is not hereditary, but genetics may still play a role. Your risk may be slightly higher if you have a family history of autoimmune disease. In gMG, the immune ...

“Six-Point” protection against heartworm, four major tick species, fleas, roundworms, hookworms, and tapeworms. The product uses four distinct agents: Lotilaner (for fleas/ticks), Moxidectin (for ...

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in ...

Neurological autoimmune diseases happen when the immune system attacks the central nervous system (CNS) or peripheral nervous system (PNS). This can cause neurological symptoms, and about 30 ...

PSEN1 encodes presenilin-1, a subunit of γ-secretase, the aspartyl protease responsible for Aβ generation. More than 300 mutations in PSEN1 have been reported and mutations in PSEN1 are the most ...

Some of the highlights in the pancreatic cancer field in 2025 include long-term data on personalized neoantigen vaccine approaches in resected pancreatic adenocarcinoma, detailed clinico-genomic ...