Eraglusib with gemcitabine and nab-paclitaxel achieved statistical significance in the first-line treatment of metastatic ...

Inhibition of GSK-3β may inhibit tumor growth and improve survival through several complimentary mechanisms that include enhancement of chemotherapy activity, activation of innate anti-tumor immunity, ...

Elraglusib is a novel inhibitor of glycogen synthase kinase-3 beta (GSK-3β), which is believed to play a role in tumor growth and chemotherapy resistance. By inhibiting this enzyme, elraglusib ...

Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death.

Targeted Oncology provides news, videos, and reviews on the rapidly evolving world of targeted therapies and immunotherapy ...

University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin ...

In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...

Although switching is usually safe and well tolerated, physician judgment concerning individual patient requirements must be maintained. The dose of the first- or second-generation β blocker that ...

A rose by any other name… is still NOT a box of chocolates! Can you imagine anyone not lusting after those luscious bites of silky sweetness? : I probably won't eat them. : Because I'm on a diet ...

Blackmagic Design has released DaVinci Resolve 20 Beta 3, which adds improved character styling and labelling of MultiText layers, more responsive editing of keyframes and curves, and better subtitle ...