A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ...

As a polymeric molecule, RNA is made up of chains of nucleotides, with each nucleotide composed of a ribose sugar group ... and providing structure. Three main types of RNA are involved in ...

For example, CXCL16 silencing has been shown to alleviate HIRI ... and mitochondrial function. Poly(ADP-ribose) polymerase-1 (PARP-1), a key enzyme in this process, is involved in DNA repair, ...

It is probably impossible to build this structure with a ribose sugar in place of the deoxyribose, as the extra oxygen atom would make too close a van der Waals contact. The previously published X ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Capital structure refers to the mix of funding sources a company uses to finance its assets and its operations. The sources typically can be bucketed into equity and debt. Using internally ...

This study presents a valuable finding that KDM5 inhibition activates the interferon response and antigen presentation genes in breast cancer cells through R-loops. The evidence supporting the claims ...