Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches ...

Vanda Pharmaceuticals Inc. (Vanda) today announced that the U.S. Food and Drug Administration (FDA) informed Vanda that the New Drug Application (NDA) for Bysantitm (milsaperidone) has been filed, and ...

Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA) today announced that the U.S. Food and Drug Administration (FDA) informed ...

Beta-3 adrenergic receptor agonists, like Gemtesa, are newer medicines that are used as alternatives when the anticholinergics or antimuscarinic medicines are not effective or cause side effects ...

Get Instant Summarized Text (Gist) Both activation (agonism) and blockade (antagonism) of the GIP receptor reduce body weight and food intake, but through distinct brain mechanisms. GIPR agonists ...

These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action. There are two main endocannabinoid receptors: CB1 receptors ...

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a group of drugs used to treat type 2 diabetes and sometimes obesity. GLP-1 RAs are very effective at lowering blood sugar levels.

2 University College London Hospitals NHS Foundation Trust, London, UK Background and aims Mineralocorticoid receptor antagonists (MRAs) reduce mortality and hospitalisation in heart failure with ...

Third-generation α 1-adrenergic antagonists are pharmacologically uroselective in that they are competitive antagonists for prostatic α 1A-receptors. [16,17] Blockade of these receptors relaxes ...