Objective Frailty is recognised as an emerging public health priority. However, there is still a lack of large-sample, well-designed clinical observational studies investigating frailty status among ...

Introduction Prescribing patterns for hyperopia in children vary widely among eye care providers worldwide. This scoping review aims to identify and map the current literature on optical correction ...

Objectives To identify the factors influencing professionals’ implementation of the National Institute for Health and Care Excellence (NICE) guidelines on self-harm. Design A rapid review evidence ...

Objective To validate the utilities of Berlin, STOP and STOP-BANG Questionnaires, other patient characteristics, comorbidities, Epworth Sleepiness Scale (ESS), fractional exhaled nitric oxide (FENO) ...

Objectives This study was carried out to improve patient safety in the operating theatre by the introduction of perioperative briefing and debriefing, which focused on an optimal collaboration between ...

Introduction Treatment of bipolar disorder is the focus of several clinical trials, however the understanding of the outcomes for establishing treatment effectiveness within these trials is limited.

Conclusions Adults with ID experience premature mortality and over-representation of potentially avoidable deaths. A national system of reporting of deaths in adults with ID is required. Inclusion in ...

Objectives To investigate the incidence and determinants of glaucoma in an elderly Chinese population, and clinical, mental health and economic impacts. Design This nationally representative, ...

Introduction Diabetes mellitus (DM) is a chronic metabolic disorder characterised by hyperglycaemia resulting from defects in insulin secretion, insulin action or both. As a major global health ...

Objective To identify psychological and physiological correlates of stress fracture in female endurance athletes. Design A cross-sectional design was used with a history of stress fractures and ...

Objectives This review investigates characteristics of implemented adaptive design clinical trials and provides examples of regulatory experience with such trials.