Previous studies reported that CPB modifies vancomycin pharmacokinetic parameters. Objective: To investigate intraoperative vancomycin pharmacokinetic changes in a large population of patients ...

Vancomycin (as HCl) 500mg/vial, 1g/vial; lyophilized pwd for IV infusion after reconstitution and dilution. The bactericidal action of vancomycin results primarily from inhibition of cell-wall ...

The aim of our study was to investigate the effects of CPB on vancomycin pharmacokinetics during the surgical phase until wound closure. The strong point of the present study is that it was the ...