I started a statin to lower my cholesterol, but I never expected it to change a bowel condition I had lived with for two ...

Interleukin-6 (IL-6) is a contradictory molecule in immunology. It helps the liver regenerate after injury and protects ...

Nektar Therapeutics has been awarded $90 million in damages after a jury sided with the biotech, which had accused Big Pharma ...

The oral corticosteroid can bring swift relief from pain and swelling — but its many possible side effects and longer-term safety risks often outweigh the benefits.

I am a patient with ulcerative colitis.To keep my condition from worsening, I want to minimize irritation to my ...

Ulcerative colitis has long been framed as a disease of overactive immunity, a condition in which the immune system attacks ...

For tens of millions of Americans, digestive issues and unpredictable gut health are far more than an occasional ...

For millions of Americans, digestive issues or an unpredictable gut isn’t an occasional inconvenience — it’s a daily balancing act around what to eat and when. An estimated ...

Tvardi Therapeutics, Inc. announced the publication of preclinical data evaluating Tvardi?s STAT3 inhibitor in the International Journal of Molecular Sciences. The publication provides additional ...

In a preclinical chronic colitis model, Tvardi’s oral small molecule accumulated in the colon at approximately 8-fold higher concentrations than in plasma, at pharmacologically relevant levels, and ...

Two bowel conditions that can look very similar may be far more different than doctors previously thought. New research from the Garvan Institute of Medical Research suggests that hidden immune ...

Same integrin family, very different risk profiles: what natalizumab's boxed PML warning and vedolizumab's VARSITY win mean for choosing between them, per Dr Lana Zhovtis Ryerson.