However, because spastic paraparesis has only been described in two of four families with Δ9 variations and because it may also be associated with other PS1 missense mutations 3, the specific ...

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up to 5% of infected people will develop a type of leukemia called adult T-cell leukemia/lymphoma or a chronic neurological disease named HTLV-1 associated myelopathy/tropical spastic paraparesis.

Infection with HTLV-1 can result in leukaemia or a chronic inflammatory disease of the central nervous system (HTLV-1-associated myelopathy/tropical spastic paraparesis; HAM/TSP). A high level of ...