Gut organoids mimic the stomach, small intestine, and colon in 3D. Learn how these lab-grown models are advancing digestive ...

A new study published in eGastroenterology explores the role of gut cannabinoid receptor 1 (CB1R) in alcohol binge-induced ...

In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models ...

Researchers at the Francis Crick Institute have shown that the Cryptosporidium parasite exports a protein into infected intestinal cells, altering the gut environment and enabling the parasite to ...

Panel A depicts transcytosis across polarized epithelial cells in adults. In intestinal epithelial cells abutting the lumen of the gut, pinocytosis of IgG from the tissues allows internalization ...

Researchers have uncovered how combined alcohol intoxication and burn injuries disrupt gut bacteria and lower the production ...

difficile infection. The white areas show the cells that line the intestine (epithelial cells). In red is the MHC-II protein, which helps activate the immune system, and in blue is the nucleus of the ...

Small intestinal bacterial overgrowth (SIBO) occurs when too much of the wrong bacteria overwhelms the small intestine, causing symptoms like abdominal pain, nausea, bloating, gas, indigestion ...

This is digested by the intestinal microbiota, which produces compounds such ... the immune response was exacerbated. The epithelial cells overproduced MHC-II, which has the function of presenting ...