An interdisciplinary research team led by Professor Dr. Bent Brachvogel has examined how mitochondria influence the premature aging of the ... skeletal system using a mouse model.

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging ... skeletal system using a mouse model.

Mouse model reveals the metabolic roots of cartilage aging ... Eventually, the cartilage cells began to die, and the tissue showed clear signs of premature aging. The team found that supplementing ...

Some animal studies also show that drinking lemon water, specifically, may help prevent oxidative stress, which can lead to premature skin aging ... accelerated mouse prone 1 (SAMP1).

Challenging the Classical Model of Nuclear Organization To decipher the mechanisms of this reorganization, the researchers conducted a mid-scale perturbation screening in mouse embryos.

The findings from study could have broad implications: in diseases such as Progeria, a genetic disorder causing premature aging, significant disruptions occur in DNA associated with the nuclear ...

Genes Dev, 7, 798-803. [80] Marino, Ugalde, Salvador-Montoliu, Varela, Quiros, Cadinanos, van der Pluijm, Freije, and Lopez-Otin (2008) Premature aging in mice activates a systemic metabolic response ...

Preliminary studies in mouse models have shown that increasing supplements ... or NR can extend healthspan—defined as years lived in good health—and reduce premature aging, according to Renae Thomas, ...