Placebo testing has been part of the process since the 1940s. It’s unclear what additional measures would achieve — but it may slow development.

An open-label study of 12 individuals with severe treatment-resistant depression found that their symptoms significantly ...

Data from an open-label trial showed that foralumab treatment eased fatigue and lessened disability for some people with ...

The use of an investigational topical BRAF-inhibiting gel appeared to be effective in treating acneiform rash in patients ...

Topical BRAF inhibitor LUT014 gel significantly reduces acneiform rash from anti-EGFR therapies in patients with colorectal ...

They say the authors’ rigorous methodology to compare the magnitude and duration of placebo and nocebo effects in pain perception yields compelling evidence that nocebo responses demonstrate ...

Results from the first patient cohort (N=5) of an open-label proof of concept academic study with low-dose IL-2 and CTLA4-Ig demonstrated a rapid and durable statistically significant increase in ...

As such, the notion of a non-pharmacological, side-effect-free intervention — like an open-label placebo — is particularly attractive. The study also prompts a broader conversation about how ...

In this preregistered study, Kunkel and colleagues set out to compare the magnitude and duration of placebo versus nocebo effects in healthy volunteers, and also to examine the different factors ...

Open-label placebo studies show that participants ... but in how it invites us to harness the placebo effect as a tool for everyday change. References Benedetti, F. (2014). Placebo effects ...