“During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity ...

Despite the increasing knowledge of the molecular basis of tissue morphogenesis, how the activity of these signaling pathways is translated into changes in cell behavior and how cell shape changes ...

Researchers from the University of Manchester have determined that the process of cell division does not always occur ...

During morphogenesis—the process by which living organisms take shape—cells collectively position themselves in specific ways, leading to the development of tissues and organs.

Gumbiner, B. M. Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84, 345–357 (1996). Gumbiner, B. M. Regulation of cadherin-mediated adhesion in morphogenesis.

What cellular mechanisms govern early morphogenesis of epithelial appendages? Are they conserved across organs? How are they perturbed in ectodermal dysplasias? What molecular pathways govern mammary ...

Progenitor cells that will contribute to formation of specific heart tissues are derived from distinct regions of the ...

Molecular genetic approaches are applied to the cell and developmental biology of model systems in order to understand how cells work in health and disease. Our interests include signal transduction, ...