Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13) of all antibacterial drugs undergoing development in Phase II trials or later ...

Although structure-based drug discovery is still in its infancy for antibacterial-drug discovery, the growing number of molecular targets for which structural information is available makes this ...

Researchers at the University of Liège (BE) have designed a high-performance, open-access continuous flow process to safely produce key antibacterial drugs from bio-based furfural. The results of the ...