To address this problem, antibody engineers introduced a serine-to-proline substitution that made the middle hinge region more like that found in IgG1 (ref. 7). This not only gave a more ...

DelveInsight’s Non-Hodgkin Lymphoma pipeline report depicts a robust space with 200+ Non-Hodgkin Lymphoma companies working ...

How malaria parasites exploit mechanism for escaping elimination could provide novel strategies targeting chronic malaria ...

Meanwhile, the Fc region (or "stem") of the antibody attaches to other immune cells. These include phagocytes, which engulf infected cells, and natural killer cells, which perforate and poison them.

Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the ...

Cells have a trick called splicing. They can cut a gene's message into pieces and decide which fragments to keep. By mixing ...

A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional ...

EpiBiologics, a leader in tissue-selective extracellular protein degradation, today presented the first preclinical data on its EpiTAC bispecific antibody degrader of c-Met, a potential first-in ...

But as Mr. Trump arrives in the Middle East next week, the fate of the region could hinge on their relationship. By Michael D. Shear Michael Shear has written about the relationships between ...