Structure activity relationship studies reveal that minimal modifications to the dimethylaniline moiety of S656 improve its cyclin K MGD function over CDK inhibition by promoting DDB1 engagement. This ...

N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ion channels present at most excitatory synapses in the brain that play essential roles in cognitive functions including learning and memory ...

Applicable infrared instrumentations: infrared (IR) oven modified from a domestic microwave (MW) oven (a), homemade reactor equipped with Osram IR heater lamp (b) as devised by Pool and Teuben, 9 and ...

Institut de Chimie des Substances Naturelles (ICSN), CNRS UPR 2301, Université Paris-Saclay, 1 Avenue de La Terrasse, 91198 Gif-sur-Yvette Cedex, France ...

Center for Continuous Flow Synthesis and Processing (CCFLOW), Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, A-8010 Graz, Austria ...