The idea that 'pain equals effectiveness' was a misconception

When performing treatments, I notice that reactions to pain vary greatly from patient to patient. Some people wince at the ...
The Lancet

Pain management in chronic pancreatitis: beyond opioids

Chronic pancreatitis is characterised by complex, multifactorial pain affecting 80–90% of patients. Pain arises from overlapping nociceptive and neuropathic mechanisms, often accompanied by CNS ...

Pain is an 'output,' not an 'input.' The true nature of chronic symptoms with 'no abnormalities in tests' and the mechanism of central sensitization

Introduction: The instrument is normal. It might be the amplifier that is brokenMy whole body hurts. I am strangely tired. Smells make me bedridden. Sounds and lights are painful. Yet, tests show 'no ...
CBC.ca

Family of missing B.C. mountaineer believes she fell during Matterhorn descent

The audio version of this article is generated by AI-based technology. Mispronunciations can occur. We are working with our partners to continually review and improve the results. The family of famed ...
Nature

Stress-Induced Pain Modulation Mechanisms articles from across Nature Portfolio

Hyperalgesia is an exaggerated response to noxious stimuli produced by peripheral or central plasticity. Stress modifies nociception, and humans with post-traumatic stress disorder (PTSD) exhibit ...