The m6A sites on FASN mRNA were tested via MeRIP-qPCR. Protein co-immunoprecipitation (Co-IP) assay was used to validate the combination between YTHDF3 and eukaryotic translation initiation factor 4A3 ...

for the FP competition kinetic assay using Orf9b 4xSGG fusion construct. E. Model parameters used for solving ODE in Berkeley Madonna for both Δ91-97 and 4xSGG constructs. F. Co-immunoprecipitation ...

Co-immunoprecipitation assays reveal that E1 interacts directly with key signaling molecules within these pathways. E1 also impairs TBK1 and IRF3 phosphorylation and obstructs the nuclear ...

(A) Co-immunoprecipitation of FLp53-FLAG ... We complemented the immunoblotting assays with immunofluorescence assays. Our results clearly show the co-localization of FLp53 with the isoforms Δ133p53 ...

Here, through in silico and in vitro screenings we identified FBXW7 as the E3 ligase involved in proteasomal degradation of HDAC4, and its role was confirmed by means of ubiquitin ...

Protein-protein interactions between PCNA and PARP1 were validated through co-immunoprecipitation and functional assays. The sensitivity of HCC cells to the PARP1 inhibitor Olaparib was evaluated ...

Zinc (Zn) is a vital micronutrient for all living organisms, and its deficiency can adversely impact crop yield and quality.

Hepatocellular carcinoma (HCC) is a common malignant tumor and the third leading cause of cancer-related mortality. The lack ...

AbraSilver Resource (TSX: ABRA) said assay results from drilling at its La Coipita copper and gold property in Argentina showed the presence of a significant porphyry system with expansion potential.

This helps CAR-T developers accelerate assay validation and lot release, while avoiding the operational burden, variability and chain-of-custody challenges of custom cell lines. "As cell and gene ...