Microscopic command centers in our bodies called primary cilia—once thought irrelevant—could be hidden switches powering ...

25, 2025 — In recent years, cell therapies have developed alongside chemotherapy and immunotherapy to become a new pillar in the treatment of patients with blood and lymph gland cancer.

YAP, a protein known to help cancer cells survive treatment, behaves very differently in cell culture models depending on how they are grown in the lab, highlighting the importance of mimicking tumour ...

HT-KIT, a novel targeted therapy for GIST, demonstrated the ability to reduce tumor burden in humanized mouse models and induce tumor cell death.

Our body's own defense system not only clears away bacteria and viruses, it can also fight cancer. However, not all tumor ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

This paper investigates how isoform II of transcription factor RUNX2 promotes cell survival and proliferation in oral squamous cell carcinoma cell lines. The authors used gain and loss of function ...

Damo Panda, an AI model used for early pancreatic cancer screening, has been officially designated as a breakthrough device by the US Food and Drug Administration (FDA), said its developer Alibaba ...

The patent covers antisense oligomers targeting the KIT gene, known to play a role in various cancers ... aimed at treating pruritus associated with EGFR inhibitor skin toxicities in cancer patients.

The strategy was particularly successful for a class of complex, large-sized drugs known as bRo5 molecules, such as PROTACs, a type of targeted cancer therapy that breaks down proteins in cells.

In contrast, the unimodal model using mammography images alone achieved an AUC of just 61.3%, underscoring the critical value of fusing clinical context with radiological data. Breast cancer subtyping ...