BACKGROUND: Limited evidence exists on the prognostic role of continuing medical therapy in patients with heart failure (HF) and an ejection fraction (EF) that has improved over time. This study ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Dropsy, described in the 17th century, treated with “cure de dechloruration” (bloodletting, leeching, and lancing) and a ...

Despite insufficient evidence to support direct-to-consumer genetic testing in routine clinical care, cardiovascular clinicians increasingly face questions about its utility and interpretation because ...

Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been well described; however, the bulk of the literature has focused on heart ...

Electronic health records (EHR) have revolutionized cardiovascular disease (CVD) research by enabling comprehensive, large‐scale, and dynamic data collection. Integrating EHR data with advanced ...

The coronary microcirculatory resistance index plays a crucial role in predicting patient prognosis. Coronary angiography‐based methods for assessing coronary microcirculatory function offer ...

Lead is an established causal risk factor for coronary heart disease. Atherosclerosis may be the key mediator for this association, but evidence from studies in humans is limited. Our objective was to ...

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Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.Z., L.H.N., S.P.J.). Department of Population Medicine, Harvard ...

Department of Medicine, Boston Medical Center, MA (S.E.C., A.V.). Department of Medicine, Section of Nephrology, Boston University Chobanian & Avedisian School of ...