This disorder can attack children from birth. Osteogenesis imperfecta also has many types with varying levels of symptoms caused. It is important to know more about this condition so that parents ...

Osteogenesis imperfecta (OI) is a heterogeneous connective tissue disorder characterized by brittle bones. Four clinical subtypes are recognized, including a mild (type I), a lethal (type II), a ...

Osteogenesis imperfecta can result in more severe complications. Signs and symptoms range from mild to severe.[1-3] There are eight types of OI, and the categorization is usually based on the ...

Both Jay and Pamela were born with osteogenesis imperfecta Type 3 (OI), which the Cleveland Clinic describes as a "genetic disease that makes your bones thin and brittle." Pamela, 30, and Jay ...

A proband with osteogenesis imperfecta (OI) type III/IV was born to clinically normal parents, who subsequently had two pregnancies terminated because of OI in the fetuses. Cultured fibroblasts ...