A novel inflammasome inhibitor derived from HIV antivirals has reversed established neurological deficits in a preclinical MS ...

Researchers at UC Berkeley have used long-term human brain organoids to show that hyperreactive astrocytes may drive the ...

City of Hope researchers have developed a modular 'plug-and-play' CAR T-cell platform that enables post-infusion ...

A preclinical study published in Myeloid Cells reports that AS01, a vaccine adjuvant system, can induce trained immunity in human monocytes and reduce tumour growth in selected mouse cancer models.

A protein can look very different in disease without a single change to its sequence. Measuring these structural changes ...

Scientists at National Jewish Health have identified oestrogen receptor alpha as a potential therapeutic target for ...

Researchers at the Salk Institute have identified a cellular pathway through which prolonged interferon exposure triggers ...

Scientists at Wake Forest University School of Medicine have uncovered a previously unrecognised cancer-intrinsic role for ...

Mayo Clinic researchers have shown that approved thyroid cancer drugs can restore a key antigen on aggressive tumour cells, making them visible once more to CAR T cells and improving treatment ...

University of Washington researchers have used stem cell-derived kidney organoids to uncover inflammatory pathways that drive ...

A bacterial enzyme produced by Bacteroides vulgatus has been shown to inactivate the intestinal hormone GLP-2, disrupting gut ...

A nasal spray using extracellular vesicles derived from the amniotic membrane has shown promise against Alzheimer's disease, ...