San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers' season finale versus the Arizona Cardinals. On San Francisco's opening series and on Guerendo's second ...

The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be ...

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the Lions.

The 49ers signed Yiadom to a one-year, $3 million deal last year to compete for their No. 3 cornerback spot. He eventually ...

Guerendo now has managed back-to-back capped sessions to kick off Week 17 prep as he looks to put foot and hamstring injuries further in the rearview mirror. He sat out the 49ers' Week 16 loss at ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN's Adam Schefter. Guerendo has been limited in practice this week ...

San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated: ACL is good, thank you GOD. I'll be back ...

A first-round tender would cost the 49ers an estimated $7,279,000 for the 2025 season according to Over the Cap. The ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ season finale in Arizona against the Cardinals with a leg injury.

The San Francisco 49ers are making a final push to close out a lost season on a strong note. Injuries have decimated the reigning NFC champs. Isaac Guerendo, however, provided a promising update.

The Detroit Lions will square off with the San Francisco 49ers on Monday Night Football in Week 17 of the NFL season at Levi’s Stadium, scheduled to start at 8:15 p.m. EST. All week, questions ...

SANTA CLARA, Calif. -- After missing last week because of a hamstring injury, San Francisco 49ers running back Isaac Guerendo is set to play Monday night against the Detroit Lions. Guerendo ...