The mammalian brain is a multiscale system. Neuronal circuitry forms an information superhighway, with some projections potentially stretching dozens of centimetres inside the brain. But those ...

The microscope combines a big telecentric photolithography lens with a large tube lens to create sharp, detailed images of large and curved samples. These lenses project the image onto a flat array of ...

A new tool aligns spatial genomic and histology data from tissue samples virtually, creating a 3D atlas from 2D slices. Using 2D tissue slices to decipher features of a 3D tissue is computationally ...

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in ...