Doesn't look like there are any revolutionary changes; same art style, same gameplay. Pick a hero (with its unique mechanic and deck of cards), move through a series of fights and events on your way ...
Hm. I hope slay the spire gets some much needed visual love. I'm not a huge fan of card games, or at least not an easy to please one. The ugly art, ugly card art, and lack of animations really kept me ...