The ability to alter the genetic composition of living cells has revolutionized biology. Scientific advances, from treating genetic disorders through gene therapy to reprograming skin cells into ...

Transfection, the delivery of nucleic acids into cells, is the core technique for enhancing or inhibiting gene expression, or for initiating the expression of nonnative proteins in host cells and ...

To explore the mechanism of hepatocarcinogenesis associated with the hepatitis B virus X protein (HBx), we investigated the role of HBx in transformation using human liver L-O2 cells stably ...

Researchers and companies are devising promising approaches to circumvent limitations of existing transfection technologies. Ongoing challenges, particularly with regard to high-quality recombinant ...

Transfection alters the genetic makeup of eukaryotic cells by introducing foreign nucleic acids, including DNA, RNA, and small noncoding RNAs such as siRNA, shRNA, and miRNA. Scientists use ...

Transfection is a process whereby foreign genetic material is introduced into eukaryotic cells. To this end, several transfection techniques have been developed. However, irrespective of the method ...

Vaccines are arguably one of the most important medical innovations in human history. When it comes to which diseases have successfully been targeted with vaccines, however, the playing field is far ...

Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...