Please provide your email address to receive an email when new articles are posted on . Few patients with cystic fibrosis have a copy of the 3849+10kb C-to-T splicing mutation. Research is planned to ...

Researchers report how mutations may contribute to inherited predisposition to cancer by altering RNA splicing. Certain genetic mutations can cause disease by altering splicing of RNA transcripts, but ...

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...

Cancers with mutations in the SF3B1 gene respond to PARP inhibitors—a type of drug used to treat cancers with mutations in the BRCA1 and BRCA2 genes, scientists at the Queen’s University of Belfast ...

Findings in Nature show that targeted therapy for mutated gene can slow or prevent tumor growth in many kinds of cancer SEATTLE — October 9, 2019 — A new, multicenter study led by Fred Hutchinson ...

Thought LeadersMaxwell Sherman Graduate Student and PhD Candidate Massachusetts Institute of Technology: MIT In this interview, News-Medical speaks to Maxwell Sherman, an MIT graduate student and one ...

Researchers in the Landau lab, led by Dr. Dan Landau, hematology and medical oncology, recently developed a new technique to investigate how mutations in RNA splicing can lead to clonal hematopoiesis ...

Researchers have determined that a mutation affecting the important process of RNA splicing can manipulate the 'quality control' in your cell. The resulting conditions characterize many deadly blood ...

Association of KRAS mutations detected via liquid biopsy in metastatic non-small cell lung cancer patients with high levels of FDG-PET SUV. This is an ASCO Meeting Abstract from the 2017 ASCO Annual ...

The protein complex cohesin is fundamental to the cell division process, as it holds sister chromatids tightly together in a ringlike structure before a cell physically splits. But now researchers at ...