Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a ...

S pecific brain cells known as layer 5 pyramidal neurons play a vital role in how our brains process information. Research by the team of Prof. Joris de Wit (VIB-KU Leuven) and colleagues ...

Using two-photon microscopy on transgenic mice, the researchers targeted the two largest populations of primary cells in the brain: pyramidal tract (PT) neurons and intratelencephalic (IT ...

(a) In the 'classical' pathway, multiple pyramidal cells (for simplicity, only one pyramidal cell is shown: P 1) excite the inhibitory interneuron (I) at its soma. The interneuron then inhibits P ...

When they compared the Purkinje cell microRNA-target map to a map for pyramidal neurons—a functionally different but similar-looking brain cell—they showed that the two cell types follow very ...