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Recent research suggests that one such difference involves tandem repeats, or short lengths of DNA that are repeated multiple times within a gene. But what, if anything, does having a different ...
In DM1, DNA strands in a gene called DMPK repeat, a process called tandem repeat expansions (TREs ... The functional errors lead to protein imbalances affecting other genes responsible for ...
Along with changes that affect protein sequence, alterations in regulatory regions make important contributions to organismal evolution. Findings in yeast now suggest that variable tandem repeat ...
The disruption causes a protein imbalance that can result in ... Gene splicing a key contributor to the development of ASD As the tandem repeat expands in the DMPK gene, the research team ...
found that as the tandem repeat expands in the DMPK gene, its altered RNA binds to a protein that is involved in gene splicing regulation during brain development. This “toxic RNA” depletes ...
The disruption causes a protein imbalance that can result in ... Gene splicing a key contributor to the development of ASD As the tandem repeat expands in the DMPK gene, the research team ...