Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the ...

Study results published in PLoS One strongly suggest machine learning can be an effective approach to identify patients who should receive a diagnostic biochemical test to screen for acute hepatic ...

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to ...

The treatment you'll get for acute hepatic porphyria (AHP) depends on your symptoms. No matter which treatment plan you and your doctor decide on, the goal is to ease symptoms and prevent ...

Acute hepatic porphyria (AHP) refers to a family of rare genetic diseases that affect the production of heme, a component of red blood cells. It can cause life threatening complications. AHP can cause ...

Porphyria is a group of genetic disorders that result in built-up of chemicals called porphyrins in the body. Porphyrins are normally converted into heme, a constituent of hemoglobin with the help of ...

Acute porphyrias are rare genetic disorders that present with neurologic and systemic symptoms, including abdominal pain, hyponatremia and seizures. When porphyria is suspected, a urine screening ...

Up-regulation of hepatic delta-aminolevulinic acid synthase 1 (ALAS1), with resultant accumulation of delta-aminolevulinic acid (ALA) and porphobilinogen, is central to the pathogenesis of acute ...

A mutation that impacts an enzyme involved in heme biosynthesis causes porphyrias, which are inheritable metabolic disorders. There are different types of porphyrias based on the specific enzyme ...

Acute intermittent porphyria (AIP) is a rare condition that causes an enzyme deficiency. This can cause a person to experience abdominal pain, nausea, vomiting, and seizures. Porphyrias are rare ...

Induction of delta aminolevulinic acid synthase 1 (ALAS1) gene expression and accumulation of neurotoxic intermediates result in neurovisceral attacks and disease manifestations in patients with acute ...

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the ...