Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding developmental processes. While not exact replicas of human organs, they ...

However, existing BBB models have been unable to replicate the complex three-dimensional 3D structure of cerebral blood vessels, posing significant challenges for research and drug development.

Experimental autoimmune encephalomyelitis (EAE) is a model of the neuroimmune ... and demyelination around blood vessels in the central nervous system (CNS), with relative sparing of nerve fibres ...