A discovery by scientists at Scripps Research and the Georgia Institute of Technology could shed light on the evolution of ...

The prebiotic Earth was a harsh and unstable environment, characterized by intense heat, active volcanoes and little atmosphere. How, then, did the molecular building blocks of life first form? Among ...

A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ADP-ribose—produced by bacteria's Thoeris II defense system in ...

It is probably impossible to build this structure with a ribose sugar in place of the deoxyribose, as the extra oxygen atom would make too close a van der Waals contact. The previously published X ...

As its name suggests, ribose has more oxygen atoms than deoxyribose. Thus, the elongation period of transcription creates a new mRNA molecule from a single template strand of DNA. As the mRNA ...

Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) are promising cancer treatments because they block a cell’s ability to repair DNA damage. Four PARPis are currently approved for use in the ...

Later it was found that the sugar in nucleic acid can be ribose or deoxyribose ... DNA was largely accepted as the genetic molecule. Scientists still needed to figure out this molecule's structure ...

Quantitative polymerase chain reaction (qPCR) is a molecular technique that has reshaped the landscape ... Locked nucleic acid (LNA) probes Probes that use modified nucleotides with a locked ribose ...

It is a polymeric molecule composed of nucleotides, each containing a ribose sugar, a phosphate group, and one of four nitrogenous bases: adenine (A), uracil (U), guanine (G), or cytosine (C). RNA is ...

Get Instant Summarized Text (Gist) A novel immune signaling molecule, histidine-ADP-ribose (His-ADPR), has been identified in bacteria's Thoeris II defense system, expanding known immune signaling ...