Advanced imaging revealed that sunitinib concentrates in lysosomes and progressively disrupts mitochondrial and endoplasmic ...

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

Investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, according to a Northwestern Medicine study published in the Journal of ...

New ICMR-NIN research shows lead exposure may disrupt nerve-cell lysosomes and worsen cellular damage linked to amyloid-beta, ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According to a ...

Lysosomes are organelles that play essential roles in cellular digestion and waste management, and lysosomal dysfunction typically leads to serious diseases. In a recent study, scientists developed a ...

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to know why. Just like the ...

What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you look for ...

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell. Now, researchers at Umeå University have revealed the ...