HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

Rather than ask “What does the liver do,” you might ask “What doesn’t the liver do?” That’s how active the liver is, with its hundreds of vital functions that have essential impacts on all organs and ...

Upon removal of the feeder layer, the cells begin to express mature hepatocytic markers (H4 antigen and CYP1AII) or acquire a bile duct-like structure, if plated on Matrigel. [86] (3) Liver ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria allows us ...

The study reveals how ER-stressed adipocytes remotely regulate UPR activation in hepatocytes through the secretion of ceramide (Cer), a fat molecule that plays a major role in cell structure ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells ...

Scientists at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out the structure of ... has been stored in liver cells. Likewise, there are ...