In the initial report describing bradykinin activity, 2 it was proposed that this substance might have a pathogenic function in shock because of its hypotensive properties. Subsequently, kinins have ...

The kallikrein–kinin system consists of the precursor kininogens, the proteolytic kallikrein enzymes, the kinin peptides (which are produced through cleavage of kininogens by kallikreins) and two ...

You've likely heard it since childhood: Don't scratch that bug bite or rash, you'll make it worse. But why would something that feels so good be bad?

Kinins were studied and characterized in terms of their physiologic and pharmacologic properties long before their chemical nature was known. Their potent effects on smooth muscles were the first ...