This core performs non-radioactive, RNA in situ hybridization (ISH) on tissue sections. A unique high-throughput technology developed by the core (Yaylaoglu MB, Titmus A, Visel A, Alvarez-Bolado G, ...

All steps of ISH – from pre-hybridization to additions of probes, hybridization, stringency washes and antibody-mediated chromogenic or fluorescent reaction – are carried out by the robotic system.

Traditionally, HER2 status has been determined by immunohistochemistry (IHC) and in situ hybridization (ISH), distinguishing ...

Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique that enables the detection and location of specific DNA sequences on chromosomes. 1 It is also used to detect the ...

(a) The basic elements of FISH are a DNA probe and a target sequence. (b) Before hybridization, the DNA probe is labeled by various means, such as nick translation, random primed labeling ...

When a species reproduces, typically, each parent passes on one of their two versions (alleles) of a given gene to their ...

Chromosomes occupy specific regions of a nucleus, called "chromosome territories." These subdomains might be doing much more than just keeping everything organized.

Researchers at Peking University have discovered that a filamentous gut fungus, Fusarium foetens, can reverse metabolic ...

A healthy 60-year-old man presented with a recurrent lesion on his left third finger after surgical treatment 7 years previously (Figure 1). A biopsy reveals squamous cell carcinoma (SCC) in situ.

Telo Genomics Corp. (TSXV: TELO) (OTCQB: TDSGF) (the "Company" or "Telo") a leader in the development of diagnostic and prognostic tests for human disease through the analysis of chromosomal telomeres ...

Precision Cancer Pathology group performs RNA in situ hybridization for formalin fixed paraffin embedded tissue sections, fixed cultured cells and fixed/frozen tissue sections. We use either ...