In 1981, the National Cooperative Gallstone Study established the efficacy and safety of CDCA therapy. [26] Although gallstones could be dissolved by oral administration of CDCA, its efficacy was low.

Gallstones are hard ... such as estrogen and progesterone, can impact bile composition. These hormones can increase the ...

are hardened deposits that form in the gallbladder, which is a small organ beneath the liver. These stones can vary in size and composition, ranging from tiny particles to larger, solid stones.