The NMR and Drug Metabolism Core has developed rapid and efficient approaches ... The half-life of a drug (t 1⁄2), absorption and tissue distribution are important properties for first-pass success of ...

An editorial in Brain Medicine calls for urgent action to address the often-overlooked toxicity of commonly prescribed drugs. A compelling editorial published in Brain Medicine highlights an emerging ...

Semaglutide - the active ingredient in medications like Ozempic and WeGovy - is only FDA approved for Type-2 diabetes, but ...

However, since over 90 percent of unmodified agomelatine is lost to first-pass liver metabolism, its use has been limited by dose-dependent liver enzyme elevations and the need for frequent liver ...