How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy ...

CCL5 protects podocytes, the kidney’s essential filtration cells, but simultaneously drives harmful inflammation. Ultimately, these damaging effects surpass its protective role, leading to progressive ...

The kidney's proximal tubule reabsorbs water, glucose, ions and other small molecules from the urine and thus maintains the ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

"The insights gained from CCL5's dual role could guide the development of cell-targeted drugs that block its harmful immune effects without interfering with its protective actions in podocytes. If ...