The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control ...

Big-picture patterns of DNA packaging, gene activation and mutations could hold the information needed to develop a blood-based biopsy for small cell lung cancer patients, according to new work ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

Link found between super-agers, or people with exceptional longevity, to inherited DNA from Ice Age hunter-gatherer ...