Combinatorial chemistry has been widely adopted by the pharmaceutical industry in the past decade. However, owing to perceived “failures” with this technology, the pharmaceutical industry has been ...

This Review discusses the theory and practices behind the generation of combinatorial antibody libraries. Such libraries give scientists unprecedented control over the antibody repertoire. They have ...

A framework based on advanced AI techniques can solve complex, computationally intensive problems faster and in a more more scalable way than state-of-the-art methods, according to a new study. A ...

Ten years ago, Stuart L. Schreiber of Harvard University and coworkers reported a technique for making natural-product-like compound collections that featured an unprecedented diversity of structures.

From drug synthesis planning and production scheduling to facility location problem, combinatorial optimization (CO) tackles decision-making over ...

Perold, André, V. Chvatal, R. L. Graham, and S. Whitesides. "Combinatorial Designs Related to the Strong Perfect Graph Conjecture." Discrete Mathematics 26, no. 2 ...