This sequential expression followed the phases of the traditional cell cycle: G0/G1 (the cell grows larger), S (the cell replicates its DNA), and G2/M (the cell prepares for division and then splits).

In somatic cells, these phases are separated by gaps ... The 'restriction point' in the mammalian cell cycle is another irreversible transition (G0–G1) that can be understood in the same ...

The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

while promoting cell cycle arrest at the G0/G1 phase and inducing apoptosis. Mechanistically, exosomal lnc-TAF12–2:1 acted as a sponge for miR-7847–3p, alleviating miRNA-mediated silencing of ...