The subjects fasted for 10 hours before SOS administration (omeprazole 20 mg in 10 mL followed by 30 mL of water) or capsule administration ... 20, 30, 40, 80, 120, 180, and 360 minutes on ...

In view of the results of this study and the direct correlation between AUC and extent of antisecretory activity, future research should address whether omeprazole ... by two 40-mg loading doses ...