Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...

Researchers at Stockholm University have succeeded in creating a molecular blueprint of how one of the world's most dangerous toxins, botulinum toxin, is structured, stabilized, delivered and released ...

UPTON, NY -- By deciphering the near atomic-level structure of the catalytic domain of botulinum toxin type E -- one of seven neurotoxins that cause botulism, a disease that paralyzes victims by ...

The toxin complex with its 14 components. The toxin itself is colored pink and sits at the top of the complex. The structure consists of tens of thousands of atoms, and here we only show the surface ...

The botulinum toxins are among the deadliest substances on Earth, and two specific toxins — including the popular drug Botox — have multiple uses for treating many neuromuscular conditions, including ...

The pathogenesis of the nerve paralysis induced by botulinum neurotoxins begins with their specific and high-affinity binding to peripheral nerve terminals. The new crystal structure of the toxin ...

Researchers have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow’s gut. Researchers from the Quadram Institute have identified genes ...

In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's powerful ...

Foodborne botulism is a potentially deadly condition that’s caused by eating food contaminated with botulinum toxin, a potent toxin that attacks the body’s nervous system. The disease is incredibly ...